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Along with other programmes the Non-Cooperation Movement urged upon the People of the sub-continent to boycott educational institutions established and administered by British Govt. and to establish National Schools, Colleges and Institutes for modern scientific education by the local people themselves.
Accordingly two Medical Schools were established in the then Bengal Province for producing National Doctors of modern medicine. One such Medical School was at Calcutta, named Calcutta National Medical Institute and the other at Dhaka, named Dhaka National Medical Institute.
The Dhaka National Medical Institute was established at Dhaka near present day Bahadur Shah Park on a land donated by Zamider Raghunath Das. Many Nationalist donated money for its construction & establishment. The First Governing Body of the Institute was formed under the chairmanship of a renowned scientist Sir Prafulla Chandra Roy KBE. The governing body included Nationalist leaders like Sir Khaza Nazim Uddin, Dr. J.C. Ghosh, Roy Bahadur Kashab Chandra Banarjee, Zamider Jogesh Chandra Das.
In 1958, the 4 years medical course (LMF) was closed by the then Provincial government of East Bengal to be replaced by 5 year medical degree course (MBBS) after I.Sc.
The Dhaka National Medical Institute could not open the 5 year medical degree course (MBBS) due to non-cooperation by the then Pakistan Govt. From the 1965 the Dhaka National Medical Institute became limited to hospital and out patient services only for the local people.
In 1971, during Liberation war of Bangladesh the Dhaka National Medical Institute Hospital was a safe shelter for the Freedom Fighter of the Liberation War.